Arie van der Ende Selected Research

Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis)

1/2022	Pneumococcal Meningitis in Adults: A Prospective Nationwide Cohort Study Over a 20-year Period.
1/2021	Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis.
12/2019	Complement factor H contributes to mortality in humans and mice with bacterial meningitis.
1/2017	pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.
1/2017	Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
1/2017	Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
3/2016	Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis.
1/2016	V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
6/2014	Streptococcus pneumoniae arginine synthesis genes promote growth and virulence in pneumococcal meningitis.
4/2014	Plasminogen activator inhibitor-1 influences cerebrovascular complications and death in pneumococcal meningitis.

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Arie van der Ende Research Topics

Disease

19	Bacterial Meningitis 01/2021 - 08/2006
18	Pneumococcal Infections 01/2022 - 04/2009
15	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 01/2022 - 09/2008
9	Meningococcal Infections 01/2022 - 08/2006
9	Meningitis 01/2021 - 01/2012
8	Infections 09/2016 - 09/2003
5	Pneumonia (Pneumonitis) 01/2017 - 11/2013
4	Sepsis (Septicemia) 01/2019 - 04/2009
3	Meningococcal Meningitis 03/2016 - 01/2012
2	Tetanus 01/2018 - 01/2018
2	Whooping Cough (Pertussis) 01/2018 - 01/2018
2	Pneumococcal Pneumonia 01/2017 - 03/2016
2	Inflammation (Inflammations) 09/2016 - 01/2016
2	Fever (Fevers) 02/2016 - 11/2014
2	Cerebral Hemorrhage 05/2013 - 01/2012
2	Disease Progression 01/2012 - 01/2012
1	Late Onset Disorders 01/2021
1	Cognitive Dysfunction 01/2021
1	Hematologic Diseases (Blood Diseases) 01/2019
1	Clinical Deterioration 01/2019
1	Atypical Hemolytic Uremic Syndrome 01/2019
1	Poliomyelitis (Polio) 01/2018
1	Diphtheria 01/2018
1	Bacteremia 01/2017
1	Sinusitis 03/2016
1	Tachycardia (Tachyarrhythmias) 03/2016
1	Cranial Nerve Diseases (Cranial Nerve Disorders) 03/2016
1	Otitis 03/2016
1	Alcoholism (Alcohol Abuse) 03/2016
1	Thymoma (Thymic Carcinoma) 01/2016
1	Subdural Empyema 07/2015
1	Hearing Loss (Hearing Impairment) 01/2015
1	Rupture 11/2014
1	Hydrocephalus (Hydrocephaly) 06/2014
1	Listeria Meningitis 06/2014
1	Seizures (Absence Seizure) 06/2014
1	Brain Edema (Cerebral Edema) 06/2014
1	Cerebral Infarction 04/2014
1	Autolysis 08/2013
1	Leukocytosis (Pleocytosis) 08/2013

Drug/Important Bio-Agent (IBA)

13	Conjugate VaccinesIBA 01/2022 - 04/2009
11	VaccinesIBA 01/2022 - 04/2009
7	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 10/2012
7	Complement System Proteins (Complement)IBA 12/2019 - 01/2010
5	10-valent pneumococcal conjugate vaccineIBA 01/2022 - 11/2015
5	CytokinesIBA 01/2017 - 04/2009
4	AntibodiesIBA 01/2017 - 01/2010
3	Polysaccharides (Glycans)IBA 01/2021 - 07/2009
3	Complement Factor H (Factor H)IBA 12/2019 - 01/2012
3	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2017 - 01/2013
3	Interleukin-6 (Interleukin 6)IBA 09/2016 - 01/2012
3	Proteins (Proteins, Gene)FDA Link 10/2011 - 08/2006
2	MenACWYIBA 01/2022 - 01/2018
2	Macrophage Migration-Inhibitory FactorsIBA 01/2021 - 03/2016
2	Immunoglobulin G (IgG)IBA 01/2018 - 03/2016
2	Serine Proteases (Serine Protease)IBA 01/2017 - 01/2017
2	Monoclonal AntibodiesIBA 01/2017 - 10/2011
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 02/2016
2	AntigensIBA 01/2017 - 11/2013
2	LipopolysaccharidesIBA 10/2014 - 06/2011
2	Biomarkers (Surrogate Marker)IBA 06/2014 - 08/2006
2	ChemokinesIBA 06/2014 - 01/2014
2	Plasminogen Activator Inhibitor 1IBA 04/2014 - 06/2007
2	AnticoagulantsIBA 05/2013 - 01/2012
2	Lipid AIBA 01/2012 - 04/2009
2	EndotoxinsIBA 01/2012 - 04/2009
2	Thromboplastin (Tissue Factor)IBA 04/2009 - 06/2007
1	insulin receptor-related receptor (IRR)IBA 01/2021
1	Diphtheria Toxoid (Vaccine, Diphtheria)FDA Link 01/2018
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 01/2018
1	Pentetic Acid (DTPA)FDA LinkGeneric 01/2018
1	Platelet Endothelial Cell Adhesion Molecule-1IBA 01/2017
1	Polymeric Immunoglobulin Receptors (Polymeric Immunoglobulin Receptor)IBA 01/2017
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 09/2016
1	Nucleosomes (Nucleosome)IBA 09/2016
1	Toll-Like Receptor 9IBA 09/2016
1	LigandsIBA 09/2016
1	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2016
1	Genetic Markers (Genetic Marker)IBA 03/2016
1	C-Reactive ProteinIBA 03/2016
1	Dynactin ComplexIBA 01/2016
1	Streptococcus pneumoniae plY proteinIBA 01/2016
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2016
1	Type V Secretion SystemsIBA 01/2016
1	Penicillins (Penicillin)FDA Link 09/2014
1	Hypnotics and Sedatives (Sedatives)IBA 06/2014
1	InterferonsIBA 06/2014
1	Endothelial Growth FactorsIBA 06/2014
1	Arginine (L-Arginine)FDA Link 06/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2014
1	Plasminogen Activators (Plasminogen Activator)IBA 04/2014
1	Coloring Agents (Dyes)IBA 08/2013
1	Vancomycin FDA LinkGeneric 08/2013
1	Complement C3 (C3 Complement)IBA 03/2013

Therapy/Procedure

10	Therapeutics 01/2022 - 10/2011
2	Antibiotic Prophylaxis 01/2021 - 11/2014
1	Contraindications 01/2019
1	Mastoidectomy 07/2015
1	Splenectomy 06/2013